Prospective comparison of positron emission tomography (PET)/magnetic resonance and PET/computed tomography dosimetry in hepatic malignant neoplastic disease after ⁹⁰Y radioembolization treatment.

ABSTRACT:

Background

⁹⁰Y radioembolization is an established treatment modality for hepatic malignancies. Successful radioembolization requires optimal dose delivery to tumors while minimizing dosages to parenchyma. Post-treatment positron emission tomography (PET)/computed tomography (CT) dosimetry is the established benchmark, whereas PET/magnetic resonance (MR) is an emerging modality. The goal of this study was to assess the intermodality agreement between PET/MR and PET/CT ⁹⁰Y dosimetry.

Methods

In this single-institution study, 18 patients (20 treatment sessions) with a primary or metastatic hepatic malignancy underwent both PET/MR and PET/CT after ⁹⁰Y radioembolization. Patients were randomized to undergo one modality first, followed by the othe

SUBMITTER: Gurajala R 

PROVIDER: S-EPMC10932664 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature