Opioid use and subsequent delirium risk in patients with advanced cancer in palliative care: a multicenter registry study.

ABSTRACT: The prevalent use of opioids for pain management in patients with advanced cancer underscores the need for research on their neuropsychiatric impacts, particularly delirium. Therefore, we aimed to investigate the potential association between opioid use and the risk of delirium in patients with advanced cancer admitted to the acute palliative care unit. We conducted a retrospective observational study utilizing a multicenter, patient-based registry cohort by collecting the data from January 1, 2019, to December 31, 2020, in South Korea. All data regarding exposures, outcomes, and covariates were obtained through retrospective chart reviews by a team of specialized medical professionals with expertise in oncology. Full unmatched and 1:1 propensity-score matched cohorts were formed, and stra

SUBMITTER: Yoo SH 

PROVIDER: S-EPMC10933309 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature