Obesity Paradox in Heart Failure with Mildly Reduced Ejection Fraction.

ABSTRACT:

Objective

The study investigates the prognostic impact of body mass index (BMI) in patients hospitalized with heart failure with mildly reduced ejection fraction (HFmrEF).

Background

Limited data regarding the prognostic impact of BMI in patients with HFmrEF is available.

Methods

Consecutive patients with HFmrEF (ie, left ventricular ejection fraction 41-49% and signs and/or symptoms of HF) were retrospectively included at one institution from 2016 to 2022. Risk stratification was performed according to WHO-defined BMI groups. The primary endpoint was all-cause mortality at 30 months (median follow-up). Kaplan-Meier, uni- and multivariable Cox proportional regression analyses were applied for statistics.

Results

1832 consecutive patients with HFmrEF were includ

SUBMITTER: Reinhardt M 

PROVIDER: S-EPMC10933520 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature