The burden of dengue and force of infection among children in Kerala, India; seroprevalence estimates from Government of Kerala-WHO Dengue study.

ABSTRACT:

Background

Dengue shows high geographic heterogeneity within and across endemic countries. In the context of increasing burden and predicted outbreaks due to climate change, understanding the heterogeneity will enable us to develop region specific targeted interventions, including vaccination. World Health Organisation (WHO) suggests standard methodologies to study the burden and heterogeneity at national and subnational levels. Regional studies with robust and standard methodology to capture heterogeneity are scarce. We estimated the seroprevalence of dengue in children aged 9-12 years and the force of infection in Kerala, India, from where Zika cases also have been reported recently.

Methods

We conducted a school-based cross-sectional survey in 38 clusters; selected by str

SUBMITTER: Indu PS 

PROVIDER: S-EPMC10934323 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature