Management of drug-resistant tuberculosis in Indonesia: a four-year cascade of care analysis.

ABSTRACT:

Background

In Indonesia, drug resistance testing for TB largely relies on Xpert MTB/RIF, and it is unknown what proportion of drug-resistant (DR) TB is adequately diagnosed and treated.

Methods

We conducted a cascade of care analysis on a cohort of presumptive rifampicin-resistant (RR) TB patients registered in 2015-2018 in a tertiary hospital in Indonesia. Estimated incidences of (presumptive) DR-TB cases were assumption-based using global reports. Data on diagnosis and consecutive cascades steps, including their timing were collected from national electronic registers, and medical records. We described a secondary cascade for patients receiving treatment not supported by phenotypic drug susceptibility testing (pDST). Factors associated with delay and loss between diagnosis

SUBMITTER: Lestari BW 

PROVIDER: S-EPMC10934335 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature