Ontology highlight
ABSTRACT:
SUBMITTER: Lang X
PROVIDER: S-EPMC10935089 | biostudies-literature | 2024 Feb
REPOSITORIES: biostudies-literature
Lang Xiaoya X Zhong Chao C Su Lingqing L Qin Manman M Xie Yanfei Y Shan Dan D Cui Yaru Y Shi Min M Li Min M Quan Hexiu H Qiu Liang L Zhong Guoyue G Yu Jun J
Molecules (Basel, Switzerland) 20240229 5
Endothelial pro-inflammatory activation is pivotal in cardiac ischemia-reperfusion (I/R) injury pathophysiology. The dried flower bud of <i>Edgeworthia gardneri</i> (Wall.) Meisn. (EG) is a commonly utilized traditional Tibetan medicine. However, its role in regulating endothelium activation and cardiac I/R injury has not been investigated. Herein, we showed that the administration of EG ethanolic extract exhibited a potent therapeutic efficacy in ameliorating cardiac endothelial inflammation (< ...[more]