Synthetic Modifications of a Pb²⁺-Sensor Acridono-Crown Ether for Covalent Attachment and Their Effects on Selectivity.

ABSTRACT: Because of environmental impact, there is a great need for chemosensors, especially for toxic heavy metals such as lead. The conventional instrumental analytical techniques rarely provide an available real-time sensing platform, thus the development of highly selective and stable synthetic chemosensor molecules is of great importance. Acridono-18-crown-6 ethers have such properties, and much research has proven their outstanding applicability in various supramolecular devices. In this present work, we aimed to enable their covalent immobilization capability by synthesizing functionalized derivatives while preserving the favored molecular recognition ability. Several new macrocycle analogues were synthesized, while synthetization difficulties and design aspects were also dealt with. The sel

SUBMITTER: Vezse P 

PROVIDER: S-EPMC10935152 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature