Rhodococcus infection: a 10-year retrospective analysis of clinical experience and antimicrobial susceptibility profile.

ABSTRACT: Rhodococcus equi is an opportunistic pathogen known to cause pulmonary and extrapulmonary disease among immunocompromised patients. Treatment is frequently challenging due to intrinsic resistance to multiple antibiotic classes. While non-equi Rhodococcus spp. are prevalent, their clinical significance is poorly defined. There is also limited data on antibiotic susceptibility testing (AST) of Rhodococcus infection in humans. We conducted a single-center, retrospective cohort study evaluating clinical characteristics, microbiologic profile, and AST of Rhodococcus infections between June 2012 and 2022 at our tertiary academic medical center. Identification of Rhodococcus spp. was performed by Sanger 16S rRNA gene sequencing and/or matrix-assisted laser desor

SUBMITTER: Ranganath N 

PROVIDER: S-EPMC10935630 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature