Breast composition during and after puberty: the Chilean Growth and Obesity Cohort Study.

ABSTRACT:

Background

Breast density (BD) is a strong risk factor for breast cancer. Little is known about how BD develops during puberty. Understanding BD trajectories during puberty and its determinants could be crucial for promoting preventive actions against breast cancer (BC) at early ages. The objective of this research is to characterize % fibroglandular volume (%FGV), absolute fibroglandular volume (AFGV), and breast volume (BV) at different breast Tanner stages until 4-year post menarche in a Latino cohort and to assess determinants of high %FGV and AFGV during puberty and in a fully mature breast.

Methods

This is a longitudinal follow-up of 509 girls from low-middle socioeconomic status of the Southeast area of Santiago, recruited at a mean age of 3.5 years. The inclusion cri

SUBMITTER: Pereira A 

PROVIDER: S-EPMC10935788 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature