Global burden, risk factors, and trends of non-Hodgkin lymphoma: A worldwide analysis of cancer registries.

ABSTRACT:

Background

Non-Hodgkin lymphoma (NHL) accounts for 90% of all malignant lymphomas. This study aimed to evaluate the global incidence, mortality, associated risk factors, and temporal trends of NHL by sex, age, and country.

Methods

Data from 185 countries globally were used for analysis. NHL incidence and mortality were collected via the GLOBOCAN (2020), CI5 series I-X, WHO mortality database, the Nordic Cancer Registries, and the SEER Program. The WHO Global Health Observatory provided country-level, age-standardized prevalence of lifestyle and metabolic risk factors. Trends were examined and reported based on average annual percentage change (AAPC) calculated using Joinpoint regression analysis. Incidence and AAPC are based on data for the last 10 years across countries.

SUBMITTER: Huang J 

PROVIDER: S-EPMC10935876 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature