Cost-effectiveness of screening for chronic kidney disease using a cumulative eGFR-based statistic.

ABSTRACT:

Objectives

Routine screening for chronic kidney disease (CKD) could enable timely interventions to slow down disease progression, but currently there are no clinical guidelines for screening. We aim to evaluate the cost-effectiveness of screening for CKD using a novel analytical tool based on a cumulative sum statistic of estimated glomerular filtration rate (CUSUMGFR).

Methods

We developed a microsimulation model that captured CKD disease progression, major complications, patients' awareness, and treatment adherence for a nationally representative synthetic cohort of age ≥ 30 years in the United States. In addition to the status quo with no screening, we considered four CUSUMGFR-based universal screening policies by frequency (annual or biennial) and starting age (30 or 60

SUBMITTER: Zafarnejad R 

PROVIDER: S-EPMC10936848 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature