Relationship between syringomyelia and myxomatous mitral valve disease in Cavalier King Charles spaniels.

ABSTRACT:

Background

Syringomyelia (SM) and myxomatous mitral valve disease (MMVD) are highly prevalent in Cavalier King Charles spaniels (CKCS). Cardiac status in CKCS with and without SM is currently unknown.

Objectives

To investigate the association between SM and MMVD severity in CKCS and CKCS with SM with and without clinical signs of SM.

Animals

Fifty-five CKCS: 40 with SM (22 symptomatic and 18 asymptomatic) and 15 without SM.

Methods

A combined retrospective and prospective study. MRI and echocardiography were used to diagnose SM and MMVD, respectively. The association between SM and MMVD severity (left ventricle internal diameter in diastole normalized to bodyweight [LVIDDN] and left atrium to aortic ratio [LA/Ao]) were tested using multivariable linear regressi

SUBMITTER: Bach MBT 

PROVIDER: S-EPMC10937514 | biostudies-literature | 2024 Mar-Apr

REPOSITORIES: biostudies-literature