House dust mite sublingual allergen immunotherapy tablet is safe and well-tolerated in Dutch clinical practice.

ABSTRACT:

Background

Half (49%) of clinically diagnosed allergic rhinitis (AR) patients are sensitized to house dust mite (HDM). If allergen avoidance and symptomatic medication fail, allergen immunotherapy may be indicated.

Objective

We investigated safety and tolerability of HDM-sublingual immunotherapy by HDM-SLIT tablets in Dutch daily clinical practice.

Methods

Daily intake of 12 SQ-HDM SLIT-tablet was investigated in a prospective, multicenter, observational study (EUPAS43753). It comprised 4 consultations in 1 year. Data on safety, tolerability, treatment satisfaction, symptomatic medication, compliance, and clinical effectiveness (Control of Allergic Rhinitis and Asthma Test; CARAT) were collected. Descriptive and longitudinal regression data analysis were performed.

SUBMITTER: Tempels-Pavlica Z 

PROVIDER: S-EPMC10937523 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature