Inspecting mother-to-infant microbiota transmission: disturbance of strain inheritance by cesarian section.

ABSTRACT:

Introduction

The initial acquisition and subsequent development of the microbiota in early life is crucial to future health. Cesarean-section (CS) birth is considered to affect early microbial transmission from mother to infant.

Methods

In this study, we collected fecal samples from 34 CS infants and their mothers from West China Second Hospital, Sichuan University to assess the microbiota developmental trajectory of mothers and infants. We explored mother-infant gut microbiome transmission via comparison with corresponding Finnish data.

Results

Metagenomic analysis of gut microbiota profiles indicated that the communities of mothers and infants were distinct. The composition of the infant gut microbiome was highly variable but also followed predictable patterns in th

SUBMITTER: Yang R 

PROVIDER: S-EPMC10937581 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature