Prognostic value of near-infrared spectroscopy regional oxygen saturation and cerebrovascular reactivity index in acute traumatic neural injury: a CAnadian High-Resolution Traumatic Brain Injury (CAHR-TBI) Cohort Study.

ABSTRACT:

Background

Near-infrared spectroscopy regional cerebral oxygen saturation (rSO₂) has gained interest as a raw parameter and as a basis for measuring cerebrovascular reactivity (CVR) due to its noninvasive nature and high spatial resolution. However, the prognostic utility of these parameters has not yet been determined. This study aimed to identify threshold values of rSO₂ and rSO₂-based CVR at which outcomes worsened following traumatic brain injury (TBI).

Methods

A retrospective multi-institutional cohort study was performed. The cohort included TBI patients treated in four adult intensive care units (ICU). The cerebral oxygen indices, COx (using rSO₂ and cerebral perfusion pressure) as well as COx_a (using rSO₂ and ar

SUBMITTER: Gomez A 

PROVIDER: S-EPMC10938687 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature