Menopausal vasomotor symptoms and plasma Alzheimer disease biomarkers.

ABSTRACT:

Background

Identifying risk factors for Alzheimer disease in women is important as women compose two-thirds of individuals with Alzheimer disease. Previous work links vasomotor symptoms, the cardinal menopausal symptom, with poor memory performance and alterations in brain structure, function, and connectivity. These associations are evident when vasomotor symptoms are monitored objectively with ambulatory skin conductance monitors.

Objective

This study aimed to determine whether vasomotor symptoms are associated with Alzheimer disease biomarkers.

Study design

Between 2017 and 2020, the MsBrain study enrolled 274 community-dwelling women aged 45 to 67 years who had a uterus and at least 1 ovary and were late perimenopausal or postmenopausal status. The key exclusion c

SUBMITTER: Thurston RC 

PROVIDER: S-EPMC10939914 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature