Randomized Prospective Trial of Epidural Analgesia after Open Hepatectomy.

ABSTRACT:

Objective

To evaluate whether patient-controlled epidural analgesia (PCEA) improves postoperative pain during ambulation following elective open hepatectomy.

Background

Strategies to alleviate postoperative pain are a critical element of recovery after surgery. However, the optimal postoperative pain management strategy following open hepatectomy remains unclear.

Methods

We conducted a prospective, nonblinded, randomized comparison of PCEA (intervention) versus intravenous patient-controlled analgesia (IV PCA; control) for postoperative pain following elective open hepatectomy. The primary end point was pain during ambulation on postoperative day (POD) 2. The study was powered to detect a clinically significant 2-point difference on the pain numeric rating scale (NRS)

SUBMITTER: Arslan-Carlon V 

PROVIDER: S-EPMC10939918 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature