Measurement of neuropeptide Y with molecularly imprinted polypyrrole on carbon fiber microelectrodes.

ABSTRACT: The measurement of neuropeptides using small electrodes for high spatial resolution would provide us with localized information on the release of neuromolecules. The release of Neuropeptide Y (NPY) is related to different neurological diseases such as stress, obesity, and PTSD, among others. In this conference paper, we electrodeposited polypyrrole on carbon fiber microelectrodes in the presence of NPY to develop a molecularly imprinted polypyrrole sensitive to NPY. Optimization of the electrodeposition process resulted in the full coverage of the polymer with nucleation sites on the carbon fiber ridges, achieving completion by the seventh cycle. Electrodeposition was performed for five cycles, and using cyclic voltammetry (CV), we studied the change in the oxidation current peak for polyp

SUBMITTER: Lopez L 

PROVIDER: S-EPMC10940184 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature