Long-term outcomes of liver transplantation for biliary atresia and results of policy changes: over 20 years of follow-up experience.

ABSTRACT:

Objective

Biliary atresia (BA) patients develop chronic liver disease after the Kasai operation and are eventually indicated for liver transplantation (LT). The purposes of this study were to analyze long-term outcomes after LT and risk factors that affect complications to reduce graft failure.

Study design

Overall, 145 pediatric patients who underwent LT between June 1996 and June 2020 after a diagnosis of BA were included. We performed a retrospective analysis of medical records and evaluated patient and graft survival, cumulative incidence of complications, risk factors, and the results of policy changes.

Results

Patient and graft survival rates in over 20 years were 95.8% and 91.0%, respectively. Post-transplantation lymphoproliferative disease was frequently obse

SUBMITTER: Kwon Y 

PROVIDER: S-EPMC10940458 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature