Cross-sectional analysis of use of real-world data in single technology appraisals of oncological medicine by the National Institute for Health and Care Excellence in 2011-2021.

ABSTRACT:

Objectives

This study aims to identify how real-world data (RWD) have been used in single technology appraisals (STAs) of cancer drugs by the National Institute for Health and Care Excellence (NICE).

Design

Cross-sectional study of NICE technology appraisals of cancer drugs for which guidance was issued between January 2011 and December 2021 (n=229). The appraisals were reviewed following a published protocol to extract the data about the use of RWD. The use of RWD was analysed by reviewing the specific ways in which RWD were used and by identifying different patterns of use.

Primary outcome measure

The number of appraisals where RWD are used in the economic modelling.

Results

Most appraisals used RWD in their economic models. The parametric use of RWD was comm

SUBMITTER: Kang J 

PROVIDER: S-EPMC10941141 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature