Outcome and Treatment of Nocardiosis After Solid Organ Transplantation: New Insights From a European Study.

ABSTRACT:

Background

Solid organ transplant (SOT) recipients are at risk of nocardiosis, a rare opportunistic bacterial infection, but prognosis and outcome of these patients are poorly defined. Our objectives were to identify factors associated with 1-year mortality after nocardiosis and describe the outcome of patients receiving short-course antibiotics (≤120 days).

Methods

We analyzed data from a multicenter European case-control study that included 117 SOT recipients with nocardiosis diagnosed between 2000 and 2014. Factors associated with 1-year all-cause mortality were identified using multivariable conditional logistic regression.

Results

One-year mortality was 10-fold higher in patients with nocardiosis (16.2%, 19/117) than in control transplant recipients (1.3%, 3/233,

SUBMITTER: Lebeaux D 

PROVIDER: S-EPMC10941331 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature