Multi-locus sequence analysis unveils a novel genus of filarial nematodes associated with ticks in French Guiana.

ABSTRACT: Filarial nematodes of the Dipetalonema lineage include tick-borne filarioids that infect both domestic and wild vertebrate hosts, but they remain understudied in many cases. In this study, we conducted a molecular characterization of a Dipetalonema-like filarioid (DLF) recently identified in two tick species in French Guiana, South America. While the cox1 mitochondrial gene was the sole marker initially sequenced for describing DLF, its classification and phylogenetic relationship with other members of the Dipetalonema lineage were unclear. Therefore, we better characterized DLF through the sequencing of six additional gene markers and conducted phylogenetic analyses. Based on this multi-locus typing scheme, DLF exhibited significant divergence from known genera and species of filarioids,

SUBMITTER: Bruley M 

PROVIDER: S-EPMC10941835 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature