An Automated Visual Psychophysics Method to Measure Visual Function in Swine Preclinical Animal Model.

ABSTRACT:

Purpose

The aim of this study was to develop and validate a test to assess visual function in pigs using the visual psychophysics contrast sensitivity function.

Methods

We utilized a touchscreen along with a pellet reward dispenser to train three Göttingen pigs on a visual psychophysics test and determined their contrast sensitivity function. Images with different contrast resolutions were used as visual stimuli and presented against a control image in a two-choice test. Following animals' acclimatization and the first phase of training, the system was arranged such that animals could self-run multiple consecutive trials without human intervention.

Results

All animals were trained within a week and remembered the task with 1 day of reinforcement when tested 1 month af

SUBMITTER: Barone F 

PROVIDER: S-EPMC10941991 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature