Dataset Information

Rendering protein structures inside cells at the atomic level with Unreal Engine.

ABSTRACT: While the recent development of cryogenic electron tomography (CryoET) makes it possible to identify various macromolecules inside cells and determine their structure at near-atomic resolution, it remains challenging to visualize the complex cellular environment at the atomic level. One of the main hurdles in cell visualization is to render the millions of molecules in real time computationally. Here, using a video game engine, we demonstrate the capability of rendering massive biological macromolecules at the atomic level within their native environment. To facilitate the visualization, we also provide tools that help the interactive navigation inside the cells, as well as software that converts protein structures identified using CryoET to a scene that can be explored with the game engine.

SUBMITTER: Chen M

PROVIDER: S-EPMC10942390 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature

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Rendering protein structures inside cells at the atomic level with Unreal Engine.

Chen Muyuan M

bioRxiv : the preprint server for biology 20240309

While the recent development of cryogenic electron tomography (CryoET) makes it possible to identify various macromolecules inside cells and determine their structure at near-atomic resolution, it remains challenging to visualize the complex cellular environment at the atomic level. One of the main hurdles in cell visualization is to render the millions of molecules in real time computationally. Here, using a video game engine, we demonstrate the capability of rendering massive biological macrom ...[more]

PMID: 38496473

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Dataset Information

Rendering protein structures inside cells at the atomic level with Unreal Engine.

Publications

Rendering protein structures inside cells at the atomic level with Unreal Engine.

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