Non-destructive visualization of internal structural changes in humidified magnesium oxide tablets using X-ray computed tomography.

ABSTRACT: Detailed examinations of the internal structure of tablets are imperative for comprehending their formulation, physical attributes, and ensuring their safe utilization. While X-ray computed tomography (CT) is valuable for noninvasively analyzing internal structural changes, the influence of humidity on these structural changes remains unexplored. Accordingly, we aimed to assess the viability of X-ray CT in non-destructively evaluating the internal structure of humidified magnesium oxide (MgO) tablets. MgO tablets were subjected to conditions of 40 °C and 75% humidity for 7 days, weighed pre- and post-humidification, and subsequently stored at room temperature (22-27 °C) until day 90. Their internal structure was evaluated using X-ray CT. We observed a substantial increase in the weight of

SUBMITTER: Amemiya T 

PROVIDER: S-EPMC10943080 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature