Abnormal occipital and frontal activity during voluntary convergence in intermittent exotropia: A task-fMRI study.

ABSTRACT: Intermittent exotropia (IXT) is characterized by intermittently outward deviation of the eye and involved with vergence dysfunction. This study aimed to investigate the brain areas related to voluntary convergence and cortical activation changes between IXT patients and normal subjects. A total of 21 subjects, including 11 IXT patients and 10 age- and sex-matched normal subjects, were recruited for this study. A voluntary convergence task was employed, with changes in brain function measured by functional magnetic resonance imaging (fMRI). Correlations between cortical activation and clinical measurements were conducted by Pearson's correlation analysis. fMRI results showed that during voluntary convergence, the medial frontal gyrus (MFG) and bilateral occipital cortex were activated in th

SUBMITTER: Xia L 

PROVIDER: S-EPMC10943311 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature