Breast Reconstruction Complications After Postmastectomy Proton Radiation Therapy for Breast Cancer.

ABSTRACT:

Purpose

Our purpose was to report complications requiring surgical intervention among patients treated with postmastectomy proton radiation therapy (PMPRT) for breast cancer in the setting of breast reconstruction (BR).

Methods and materials

Patients enrolled on a prospective proton registry who underwent BR with immediate autologous flap, tissue expander (TE), or implant in place during PMPRT (50/50.4 Gy +/- chest wall boost) were eligible. Major reconstruction complication (MRC) was defined as a complication requiring surgical intervention. Absolute reconstruction failure was an MRC requiring surgical removal of BR. A routine revision (RR) was a plastic surgery refining cosmesis of the BR. Kaplan-Meier method was used to assess disease outcomes and MRC. Cox regression was

SUBMITTER: Berlin E 

PROVIDER: S-EPMC10943514 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature