Disease-modifying therapy initiation patterns in multiple sclerosis in three large MS populations.

ABSTRACT:

Background

Treatment guidelines recommend early disease-modifying therapy (DMT) initiation after diagnosis of multiple sclerosis (MS). Multinational comparative studies that assess time to DMT initiation in MS may allow detection of barriers inherent to healthcare systems to explain potential adverse systematic delays in commencing DMTs.

Objectives

To investigate and compare the time to first DMT and its association with sociodemographic and clinical variables after MS diagnosis in three large MS registries.

Design

This observational study was conducted using data from the German MS Registry (GMSR), the North American Research Committee on MS Registry (NARCOMS, US data only), and the United Kingdom MS Registry (UKMSR, both self- and clinician-reported).

Methods

SUBMITTER: Stahmann A 

PROVIDER: S-EPMC10943712 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature