Porphyromonas gingivalis-induced hematogenous disseminated severe pneumonia: a case report.

ABSTRACT: Porphyromonas gingivalis, a gram-negative oral anaerobe among more than more than 500 bacterial species that colonizing the oral cavity, is involved in the pathogenesis and prototypic polybacterial consortium of periodontitis. It is mainly found in oral infections and rarely present in other organ diseases. Here, we describe a 43-year-old man with underlying diabetes who developed hematogenous disseminated severe pneumonia after P. gingivalis had invaded the blood. Next-generation sequencing of early alveolar lavage fluid and blood samples confirmed the diagnosis. The patient's lung infection improved after targeted antimicrobial treatment. He was successfully weaned from ventilatory support and transferred to the general ward. This case illustrates bacterial entry into the b

SUBMITTER: Yuanjun Z 

PROVIDER: S-EPMC10943720 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature