Antimicrobial resistance markers distribution in Staphylococcus aureus from Nsukka, Nigeria.

ABSTRACT:

Background

Multidrug resistance in Staphylococcus aureus continues to influence treatment complications in clinical settings globally. Multidrug-resistant-S. aureus (MDR-SA) is often genetically driven by resistance markers transferable in pathogenic strains. This study aimed to determine the distribution of resistance markers in clinical isolates of S. aureus in Nsukka, Nigeria.

Methods

A total of 154 clinical samples were cultured on mannitol salt agar. Isolates were characterized using conventional cultural techniques and confirmed by PCR detection of S. aureus-specific nuc gene. Antibiotic resistance profiles of the isolates were determined against selected antibiotics using the disk-diffusion method, while screening for antibiotic resistance genes (Mec A, Erm A, Erm B,

SUBMITTER: Agbo MC 

PROVIDER: S-EPMC10943768 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature