OralExplorer: a web server for exploring the mechanisms of oral inflammatory diseases.

ABSTRACT:

Background

Oral inflammatory diseases are localized infectious diseases primarily caused by oral pathogens with the potential for serious systemic complications. However, publicly available datasets for these diseases are underutilized. To address this issue, a web tool called OralExplorer was developed. This tool integrates the available data and provides comprehensive online bioinformatic analysis.

Methods

Human oral inflammatory disease-related datasets were obtained from the GEO database and normalized using a standardized process. Transcriptome data were then subjected to differential gene expression analysis, immune infiltration analysis, correlation analysis, pathway enrichment analysis, and visualization. The single-cell sequencing data was visualized as cluster plot

SUBMITTER: Lin W 

PROVIDER: S-EPMC10943789 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature