Association of Cardiac Biomarkers in Combination With Cognitive Impairment After Acute Ischemic Stroke.

ABSTRACT:

Background

Poststroke cognitive impairment is a severe and common clinical complication that constitutes a substantial global health burden. We aimed to evaluate the association of 3 cardiac biomarkers in combination with poststroke cognitive impairment and their prognostic significance.

Methods and results

This prospective study included 566 patients with ischemic stroke. Cardiac biomarkers, including sST2 (soluble suppression of tumorigenicity-2 receptor), GDF-15 (growth differentiation factor-15), and NT-proBNP (N-terminal pro-B-type natriuretic peptide), were measured. Cognitive impairment was defined as a Mini-Mental State Examination score of <27 or a Montreal Cognitive Assessment score of <25 at 3 months after ischemic stroke. Odds of cognitive impairment 3 months aft

SUBMITTER: Yang P 

PROVIDER: S-EPMC10944059 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature