Aberrant brain dynamics of large-scale functional networks across schizophrenia and mood disorder.

ABSTRACT:

Introduction

The dynamics of large-scale networks, which are known as distributed sets of functionally synchronized brain regions and include the visual network (VIN), somatomotor network (SMN), dorsal attention network (DAN), salience network (SAN), limbic network (LIN), frontoparietal network (FPN), and default mode network (DMN), play important roles in emotional and cognitive processes in humans. Although disruptions in these large-scale networks are considered critical for the pathophysiological mechanisms of psychiatric disorders, their role in psychiatric disorders remains unknown. We aimed to elucidate the aberrant dynamics across large-scale networks in patients with schizophrenia (SZ) and mood disorders.

Methods

We performed energy-landscape analysis to investigate

SUBMITTER: Ishida T 

PROVIDER: S-EPMC10944194 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature