The relevance of the superior cervical ganglion for cardiac autonomic innervation in health and disease: a systematic review.

ABSTRACT:

Purpose

The heart receives cervical and thoracic sympathetic contributions. Although the stellate ganglion is considered the main contributor to cardiac sympathetic innervation, the superior cervical ganglia (SCG) is used in many experimental studies. The clinical relevance of the SCG to cardiac innervation is controversial. We investigated current morphological and functional evidence as well as controversies on the contribution of the SCG to cardiac innervation.

Methods

A systematic literature review was conducted in PubMed, Embase, Web of Science, and COCHRANE Library. Included studies received a full/text review and quality appraisal.

Results

Seventy-six eligible studies performed between 1976 and 2023 were identified. In all species studied, morphological evidenc

SUBMITTER: Chen HS 

PROVIDER: S-EPMC10944423 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature