Direct oral anticoagulants compared with warfarin in patients with left ventricular thrombus: a cohort study from China.

ABSTRACT:

Background

Current guidelines recommend vitamin K antagonist (VKA) for left ventricular (LV) thrombus. This study aimed to compare the effectiveness and safety of direct oral anticoagulant (DOAC) and warfarin in Chinese patients with LV thrombus.

Methods

Patients with LV thrombus admitted to Beijing Anzhen Hospital of Capital Medical University between January 2018 and January 2022, were enrolled in this cohort study. The primary endpoint was defined as thrombus resolution within 90 days. The secondary endpoints included thrombus resolution within 180 days, major bleeding events, and minor bleeding events. All patients were followed up for at least 90 days after diagnosis of LV thrombus. Patients were divided into the VKA and DOAC groups according to the anticoagulants. Diff

SUBMITTER: Zhou Y 

PROVIDER: S-EPMC10944738 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature