Identification of prognostic biomarkers of smoking-related lung cancer.

ABSTRACT:

Background

The early diagnosis and effective prognostic treatment measures for lung cancer are still limited, leading to a 5-year survival rate of less than 15% for these patients. Smoking is one of the causes of lung cancer, but it is not the initial carcinogenic factor. It is not clear what specific mechanism cigarette induces lung cancer, and there is a lack of research on the relationship between related genes and the prognosis of patients with smoking lung cancer. The objective of this study was to provide new theoretical evidence and potential therapeutic targets for the mechanisms of smoking-related lung cancer formation.

Methods

The gene expression profile data from the GSE12428 dataset which includes 63 lung cancer and normal tissue pairs were downloaded from the Ge

SUBMITTER: Liang C 

PROVIDER: S-EPMC10944783 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature