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The cell death-related genes machine learning model for precise therapy and clinical drug selection in hepatocellular carcinoma.


ABSTRACT:

SUBMITTER: Du M 

PROVIDER: S-EPMC10945081 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature

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The cell death-related genes machine learning model for precise therapy and clinical drug selection in hepatocellular carcinoma.

Du Mingyang M   Qu Yonggang Y   Qin Lingshan L   Zheng Jiahe J   Sun Wei W  

Journal of cellular and molecular medicine 20240401 7


Hepatocellular carcinoma (HCC) is the prevailing subtype of hepatocellular malignancy. While previous investigations have evidenced a robust link with programmed cell death (PCD) and tumorigenesis, a comprehensive inquiry targeting the relationship between multiple PCDs and HCC remains scant. Our aim was to develop a predictive model for different PCD patterns in order to investigate their impact on survival rates, prognosis and drug response rates in HCC patients. We performed functional annota  ...[more]

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