Communicative impairment and its neural correlates in Alzheimer's disease and frontotemporal dementia.

ABSTRACT:

Objective

Communication skills can deteriorate in neurodegenerative diseases such as Alzheimer's disease (AD) and frontotemporal dementia (FTD); however, their clinical assessment and treatment in patient care can be challenging. In the present study, we aimed to quantify the distinctive communication resources and barriers reported by patients and their relatives in AD and FTD and associated these communicative characteristics with clinical parameters, such as the degree of cognitive impairment and atrophy in language-associated brain areas.

Methods

We assessed self-reported communication barriers and resources in 33 individuals with AD and FTD through an interview on daily-life communication, using the Aachener KOMPASS questionnaire. We correlated reported communication ba

SUBMITTER: Haeger A 

PROVIDER: S-EPMC10945087 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature