Genetic basis of Arabidopsis thaliana responses to infection by naive and adapted isolates of turnip mosaic virus.

ABSTRACT: Plant viruses account for enormous agricultural losses worldwide, and the most effective way to combat them is to identify genetic material conferring plant resistance to these pathogens. Aiming to identify genetic associations with responses to infection, we screened a large panel of Arabidopsis thaliana natural inbred lines for four disease-related traits caused by infection by A. thaliana-naïve and -adapted isolates of the natural pathogen turnip mosaic virus (TuMV). We detected a strong, replicable association in a 1.5 Mb region on chromosome 2 with a 10-fold increase in relative risk of systemic necrosis. The region contains several plausible causal genes as well as abundant structural variation, including an insertion of a Copia transposon into a Toll/interleukin

SUBMITTER: Butkovic A 

PROVIDER: S-EPMC10945600 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature