Ontology highlight
ABSTRACT:
SUBMITTER: Lavezzo GM
PROVIDER: S-EPMC10945726 | biostudies-literature | 2024
REPOSITORIES: biostudies-literature
Lavezzo Guilherme Miura GM Lauretto Marcelo de Souza MS Andrioli Luiz Paulo Moura LPM Machado-Lima Ariane A
Genetics and molecular biology 20240119 4
Prediction of transcription factor binding sites (TFBS) is an example of application of Bioinformatics where DNA molecules are represented as sequences of A, C, G and T symbols. The most used model in this problem is Position Weight Matrix (PWM). Notwithstanding the advantage of being simple, PWMs cannot capture dependency between nucleotide positions, which may affect prediction performance. Acyclic Probabilistic Finite Automata (APFA) is an alternative model able to accommodate position depend ...[more]