Single neurons in the thalamus and subthalamic nucleus process cardiac and respiratory signals in humans.

ABSTRACT: Visceral signals are constantly processed by our central nervous system, enable homeostatic regulation, and influence perception, emotion, and cognition. While visceral processes at the cortical level have been extensively studied using non-invasive imaging techniques, very few studies have investigated how this information is processed at the single neuron level, both in humans and animals. Subcortical regions, relaying signals from peripheral interoceptors to cortical structures, are particularly understudied and how visceral information is processed in thalamic and subthalamic structures remains largely unknown. Here, we took advantage of intraoperative microelectrode recordings in patients undergoing surgery for deep brain stimulation (DBS) to investigate the activity of single neurons

SUBMITTER: De Falco E 

PROVIDER: S-EPMC10945861 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature