Elevated high-density lipoprotein cholesterol and adverse outcomes in women with symptoms of ischemic heart disease.

ABSTRACT:

Background

Emerging data in the general population and those with coronary artery disease demonstrate higher risk of adverse outcomes with high (>70 mg/dL) HDL-C levels. There are limited data on the risk of adverse outcomes in women with suspected ischemic heart disease.

Objective

To investigate relationships between high (>70 mg/dL), average (50-70 mg/dL), and low (<50 mg/dL) HDL-C levels with major adverse cardiac events (MACE) (death, myocardial infarction, stroke, and heart failure hospitalization), and all-cause mortality in women referred for coronary angiography for suspected myocardial ischemia.

Methods

A total of 607 women enrolled in the Women's Ischemia Syndrome Evaluation (WISE) original cohort (NCT00000554) with available HDL-C values were included in th

SUBMITTER: Ranasinghe S 

PROVIDER: S-EPMC10946010 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature