Paradoxical pulmonary artery systolic pressure response with catheter-directed therapies for pulmonary embolism.

ABSTRACT:

Background

Early data on use of catheter-directed therapies (CDT) for treatment of Intermediate or High-Risk pulmonary embolism (PE) show improvement in pulmonary artery systolic pressures (PAsP) and RV/LV ratios. Occasionally a paradoxical rise in PAsP was observed with CDT utilizing ultrasound-assisted thrombolysis (USAT). It is unclear whether this pattern is seen with CDT utilizing mechanical aspiration.

Objectives

To investigate and compare the changes in PAsP between those who underwent CDT with USAT to those with mechanical aspiration.

Methods

A retrospective analysis of those diagnosed with Intermediate or High-Risk PE who underwent CDT using USAT or mechanical aspiration from 7/2013 to 3/2023. The primary outcome was comparison of PAsP changes between the two

SUBMITTER: Ho P 

PROVIDER: S-EPMC10946050 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature