Novel percutaneous technique for creation of porcine model of tricuspid regurgitation via two routes.

ABSTRACT:

Objective

To develop an experimental porcine model of tricuspid regurgitation using two induction routes: the inferior vena cava and superior vena cava.

Methods

Tricuspid regurgitation was generated using the loop wire cutting method. The tricuspid regurgitation jet direction was controlled by accessing the valve through the inferior (n = 7) or superior (n = 6) vena cava. The occurrence, direction, and progression of tricuspid regurgitation were assessed postoperatively, and echocardiography was performed at 4 to 6 weeks. Right heart dilatation was assessed using computed tomography after 6 weeks.

Results

Moderate to severe or torrential tricuspid regurgitation occurred immediately after the procedure in 12 of 13 animals. The jet was directed toward the septum in five

SUBMITTER: Oh JS 

PROVIDER: S-EPMC10946071 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature