A Long Way to Go: A Scenario for Clinical Trials of PI3K Inhibitors in Treating Cancer.

ABSTRACT:

Background

Alterations in PI3K function are directly related to cancer, making PI3K inhibitors suitable options for anticancer therapies. Information on therapy using different types of PI3K inhibitors is available in literature, providing indications of trends in developing new therapies. Although some studies on PI3K inhibitors for cancer treatment provide clinical evidence, they do not allow a careful search for potential PI3K inhibitors conducted by development indicators. Here, we performed a foresight study of clinical trials involving PI3K inhibitors from the past 11 years using indicators of clinical evolution to identify technological trends and provide data for supporting recommendations for new study designs.

Methods

A comprehensive foresight study was designed ba

SUBMITTER: Trigueiros BAFDS 

PROVIDER: S-EPMC10946074 | biostudies-literature | 2024 Jan-Dec

REPOSITORIES: biostudies-literature