The history of families at-risk for hereditary breast and ovarian cancer: what are the impacts of genetic counseling and testing?

ABSTRACT:

Introduction

Cancer Genetic Counseling (CGC) and genetic testing (GT) assume a paramount role for hereditary cancer predisposition syndrome families. We assessed the effects of CGC and GT on women affected by cancer who are at risk for hereditary breast and ovarian cancer predisposition syndrome (HBOC).

Methods

This study encompasses four time points: before the CGC session, after the CGC session when blood is drawn for GT, after disclosure of GT results, and six months following disclosure of GT results. The impacts of CGC and GT were assessed using psychosocial questionnaires. Additionally, a pedigree, genogram, and ecomap were constructed through a semistructured interview.

Results

A total of sixty women were included in the study. Most participants considered thei

SUBMITTER: Campacci N 

PROVIDER: S-EPMC10946339 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature