Cost-effectiveness analysis of leadless cardiac resynchronization therapy.

ABSTRACT:

Background

The Wireless Stimulation Endocardially for CRT (WiSE-CRT) system is a novel technology used to treat patients with dyssynchronous heart failure (HF) by providing leadless cardiac resynchronization therapy (CRT). Observational studies have demonstrated its safety and efficacy profile, however, the treatment cost-effectiveness has not previously been examined.

Methods

A cost-effectiveness evaluation of the WiSE-CRT System was performed using a cohort-based economic model adopting a "proportion in state" structure. In addition to the primary analysis, scenario analyses and sensitivity analyses were performed to test for uncertainty in input parameters. Outcomes were quantified in terms of quality-adjusted life year (QALY) differences.

Results

The primary analy

SUBMITTER: Wijesuriya N 

PROVIDER: S-EPMC10946454 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature