Long-term exposure to low concentrations of air pollution and decline in lung function in people with idiopathic pulmonary fibrosis: Evidence from Australia.

ABSTRACT:

Background and objective

Little is known about the association between ambient air pollution and idiopathic pulmonary fibrosis (IPF) in areas with lower levels of exposure. We aimed to investigate the impact of air pollution on lung function and rapid progression of IPF in Australia.

Methods

Participants were recruited from the Australian IPF Registry (n = 570). The impact of air pollution on changes in lung function was assessed using linear mixed models and Cox regression was used to investigate the association with rapid progression.

Results

Median (25th-75th percentiles) annual fine particulate matter (<2.5 μm, PM_2.5 ) and nitrogen dioxide (NO₂ ) were 6.8 (5.7, 7.9) μg/m³ and 6.7 (4.9, 8.2) ppb, respectively. Compared to living mor

SUBMITTER: Zheng Q 

PROVIDER: S-EPMC10946479 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature