Hippocampal spatial view cells for memory and navigation, and their underlying connectivity in humans.

ABSTRACT: Hippocampal and parahippocampal gyrus spatial view neurons in primates respond to the spatial location being looked at. The representation is allocentric, in that the responses are to locations "out there" in the world, and are relatively invariant with respect to retinal position, eye position, head direction, and the place where the individual is located. The underlying connectivity in humans is from ventromedial visual cortical regions to the parahippocampal scene area, leading to the theory that spatial view cells are formed by combinations of overlapping feature inputs self-organized based on their closeness in space. Thus, although spatial view cells represent "where" for episodic memory and navigation, they are formed by ventral visual stream feature inputs in the parahippocampal gy

SUBMITTER: Rolls ET 

PROVIDER: S-EPMC10946493 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature