Trends in survival of children with severe congenital heart defects by gestational age at birth: A population-based study using administrative hospital data for England.

ABSTRACT:

Background

Children with congenital heart defects (CHD) are twice as likely as their peers to be born preterm (<37 weeks' gestation), yet descriptions of recent trends in long-term survival by gestational age at birth (GA) are lacking.

Objectives

To quantify changes in survival to age 5 years of children in England with severe CHD by GA.

Methods

We estimated changes in survival to age five of children with severe CHD and all other children born in England between April 2004 and March 2016, overall and by GA-group using linked hospital and mortality records.

Results

Of 5,953,598 livebirths, 5.7% (339,080 of 5,953,598) were born preterm, 0.35% (20,648 of 5,953,598) died before age five and 3.6 per 1000 (21,291 of 5,953,598) had severe CHD. Adjusting for GA, under

SUBMITTER: Gimeno L 

PROVIDER: S-EPMC10946523 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature